Download PDF by Beverly A. (Ed.) Teicher,Beverly A. Teicher: Cancer Drug Resistance (Cancer Drug Discovery and

By Beverly A. (Ed.) Teicher,Beverly A. Teicher

top specialists summarize and synthesize the newest discoveries in regards to the alterations that happen in tumor cells as they improve resistance to anticancer medicines, and recommend new techniques to fighting and overcoming it. The authors evaluation physiological resistance dependent upon tumor structure, mobile resistance in accordance with drug delivery, epigenetic adjustments that neutralize or skip drug cytotoxicity, and genetic adjustments that regulate drug aim molecules through lowering or taking away drug binding and efficacy. Highlights comprise new insights into resistance to antiangiogenic cures, oncogenes and tumor suppressor genes in healing resistance, melanoma stem cells, and the advance of more suitable remedies. There also are new findings on tumor immune get away mechanisms, gene amplification in drug resistance, the molecular determinants of multidrug resistance, and resistance to taxanes and Herceptin.

Show description

Read Online or Download Cancer Drug Resistance (Cancer Drug Discovery and Development) PDF

Best pharmacology books

Introduction to Food Toxicology (Food Science and by Takayuki Shibamoto,Leonard F. Bjeldanes PDF

The realm of foodstuff toxicology at the moment has a excessive profile of curiosity within the foodstuff undefined, universities, and govt organisations, and is unquestionably of significant quandary to shoppers. there are lots of books which hide chosen pollution in meals (such as plant pollutants, mycotoxins, insecticides, or heavy metals), yet this e-book represents the 1st pedagogic remedy of the whole variety of poisonous compounds chanced on certainly in meals or brought by way of business illness or meals processing equipment.

Download e-book for kindle: Compact Regs Parts 50, 54, 56, and 312: CFR 21 Parts 50, 56, by Interpharm

This book encompasses a verbatim replica of 21 CFR half 50 safety of Human matters, 21 CFR half fifty four monetary Disclosure by means of scientific Investigators, 21 CFR half fifty six Institutional evaluation forums & 21 CFR half 312 Investigational New Drug Application.

Gerinnungspatienten in der Apotheke: Basiswissen und - download pdf or read online

Herzinfarkt, Schlaganfall und Venenerkrankungen sind Volkskrankheiten unserer Zeit. Damit die Patienten mit ihrer Erkrankung intestine zurechtkommen und die Therapieziele sicher erreicht werden, müssen Gerinnungspatienten in der Apotheke kompetent betreut werden. Die Therapie mit Gerinnungshemmern wie Vitamin-K-Antagonisten gleicht einer Gratwanderung.

Download e-book for iPad: Dictionary of Pharmaceutical Medicine by Gerhard Nahler,Dominique Brunier,Annette Mollet,Michaela

This dictionary defines quite a few phrases mostly utilized in pharmaceutical medicine. A new, 4th variation comprises variations of the textual content to the gradually expanding regulatory necessities, relatively within the zone of genetics/gene treatment, product caliber (e. g. , safeguard opposed to falsified medications) and of product protection (pharmacovigilance).

Extra info for Cancer Drug Resistance (Cancer Drug Discovery and Development)

Sample text

Download PDF sample

Cancer Drug Resistance (Cancer Drug Discovery and Development) by Beverly A. (Ed.) Teicher,Beverly A. Teicher

by Kevin

Rated 4.50 of 5 – based on 21 votes