Applying Genomic and Proteomic Microarray Technology in Drug by Robert S. Matson PDF

By Robert S. Matson

Microarrays play an more and more major function in drug discovery. the economic panorama has replaced dramatically during the last few years and researchers have made nice developments with reference to development and use. Now in its moment variation, Applying Genomic and Proteomic Microarray expertise in Drug Discovery highlights, describes, and evaluates present clinical learn utilizing microarray expertise in genomic and proteomic applications.

Updated and revised to mirror contemporary development within the box, the second one variation discusses:

  • Expanded omics-driven purposes, together with the parts of metabolomics and chemical biology

  • The commercialization of the microarray platform, with a historic point of view geared toward spotting key technological developments

  • Solid-supports (substrates) and floor chemistries presently utilized in the construction of nucleic acid and protein microarrays

  • Different techniques to generating microarrays that in attaining spot equality with a similar variety of molecules accurately oriented

  • The improvement of the gene expression microarray and consultant applications

  • The improvement of protein microarray know-how, together with its historical past and key applications

Unique to this variation is a brand new bankruptcy on multiplex assays that examines the advance and functions of arrays throughout various systems. It discusses functions for qPCR, multiplex lateral movement, and multiplex bead assays. It additionally provides platform-to-platform comparisons.

Microarrays stay a useful instrument for omics-based study not just in drug discovery, yet within the existence sciences, in medical study, and for diagnostic functions world wide. This quantity offers the present cutting-edge at the software of this expertise to unravel a number of significant organic problems.

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Applying Genomic and Proteomic Microarray Technology in Drug Discovery, Second Edition by Robert S. Matson

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